The Scientific Resource Center is a coordinating center for a large, multi-center federal program that collectively aims to synthesize evidence to inform medical decisionmaking. We are a centralized resource for scientific, medical, editorial, and technical expertise to promote scientific rigor, and consistency within the Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC) program.

Primary functions

We support the production of EPC evidence reviews from conception, through production, and into publication and dissemination. We work with medical decision makers to transform their decisional dilemmas into research questions and assist AHRQ in prioritizing those research questions for funding.

We help to ensure methodological consistency and rigor across EPCs by facilitating workgroups, and we promote collaboration and expansion of skills by hosting program-wide meetings. We develop templates and resources to promote consistency across the EPCs. We are essential in the editorial oversight of EPC evidence reviews, both by providing direct editorial input and managing the recruitment and activities of peer reviewers. We have innovated and piloted a more modern web-based presentation for EPC reviews ("NxGen") and are assisting AHRQ in the implementation of this new report format.


In addition to AHRQ and the EPCs, we work with a variety of stakeholders in the field of evidence-based medicine, including guideline developers, federal partners, clinicians, and patient advocacy groups, as well as health systems and practices, particularly learning health systems. We also support those who come to our program with medical decisional dilemmas, working to ensure they are provided with evidence products designed to inform their decisions. We work to collaborate with external experts in the field of evidence reviews to ensure EPC reports are using the most up-to-date and rigorous methodology so end-users of AHRQ EPC products can trust in the findings.

SRC Goals

SRC Core Values

About Us

The Scientific Resource Center (SRC) is located at the Portland Veterans Administration Hospital campus in beautiful, sunny Portland, Oregon.

The SRC was created and contracted in 2005 at the request of the Agency for Healthcare Research and Quality (AHRQ) to support its Evidence-based Practice Center (EPC) program.

The SRC is funded under a contract from the AHRQ EPC program ( and is located at the Portland VA Research Foundation

We can be reached by email at