Recent Publications and Presentations

The Scientific Resource Center (SRC) publishes and presents on issues relevant to the content, methods, and presentation of systematic and comparative effectiveness review. A listing of our most recent and most important work follows:

Highlighted Publications (5)

Journal Manuscripts (20)

1.	Antibody Response After SARS-CoV-2 Infection and Implications for Immunity: A Rapid Living Review	Annals of Internal Medicine	https://doi.org/10.7326/M20-7547
2.	Risk for Reinfection After SARS-CoV-2: A Living, Rapid Review for American College of Physicians Practice Points on the Role of the Antibody Response in Conferring Immunity Following SARS-CoV-2 Infection	Annals of Internal Medicine	https://doi.org/10.7326/M21-4245
3.	Adam GP, Balk EM, Jap J, et al. AHRQ EPC Series on improving translation of evidence: Web-based interactive presentation of systematic review reports.	Joint Commission Journal on Quality and Patient Safety	https://dx.doi.org/10.1016/j.jcjq.2019.05.001
4.	Barclay C, Viswanathan M, Ratner S, et al. AHRQ EPC Series on implementing evidence-based screening and counseling for unhealthy alcohol use with Epic-based electronic health record tools.	Joint Commission Journal on Quality and Patient Safety	https://dx.doi.org/10.1016/j.jcjq.2019.05.009.
5.	Borsky AE, et al. AHRQ EPC Series on improving translation of evidence: perceived value of translational products by the AHRQ EPC Learning Health Systems Panel.	Joint Commission Journal on Quality and Patient Safety	https://doi.org/10.1016/j.jcjq.2019.08.002
6.	Fiordalisi C, et al. AHRQ EPC Series on improving translation of evidence into practice for the learning health system: introduction.	Joint Commission Journal on Quality and Patient Safety	https://doi.org/10.1016/j.jcjq.2019.05.006
7.	Flores EJ, Jue JJ, Giradi G, et al. AHRQ EPC Series on improving translation of evidence: Use of a clinical pathway for c. difficile treatment to facilitate the translation of research findings into practice.	Joint Commission Journal on Quality and Patient Safety	https://doi.org/10.1016/j.jcjq.2019.10.002.
8.	Guise, JM, et al. AHRQ EPC Series on improving translation of evidence: Progress and promise in supporting learning health systems.	Joint Commission Journal on Quality and Patient Safety	https://doi.org/10.1016/j.jcjq.2019.10.008
9.	White CM, Coleman CI, Jackman K, et al. AHRQ EPC series on improving translation of evidence: Linking evidence reports and performance measures to help learning health systems use new information for improvement.	Joint Commission Journal on Quality and Patient Safety	https://doi.org/10.1016/j.jcjq.2019.05.002.
10.	Retention Strategies for Medications for Addiction Treatment in Adults with Opioid Use Disorder: A Rapid Review	Journal of Addiction Medicine	https://doi.org/10.1097/adm.0000000000000739
11.	Agency for Healthcare Research and Quality Evidence-based Practice Center methods provide guidance on prioritization and selection of harms in systematic reviews	Journal of Clinical Epidemiology	https://doi.org/10.1016/j.jclinepi.2018.01.007
12.	Murad MH, Chang SM, Fiordalisi C, et al. Improving the Utility for Healthcare Decisionmakers of Evidence Synthesis in the Face of Insufficient Evidence	Journal of Clinical Epidemiology	https://doi.org/10.1016/j.jclinepi.2021.02.028
13.	Paynter RA, Featherstone R, Stoeger E, et al. A Prospective Comparison of Evidence Synthesis Search Strategies Developed With and Without Text-Mining Tools	Journal of Clinical Epidemiology	https://doi.org/10.1016/j.jclinepi.2021.03.013
14.	Recommendations for assessing the risk of bias in systematic reviews of health-care interventions	Journal of Clinical Epidemiology	https://doi.org/10.1016/j.jclinepi.2017.12.004
15.	Lin JS, Murad MH, Leas B, et al. A Narrative Review and Proposed Framework for Using Health System Data with Systematic Reviews to Support Decision-making.	Journal of General Internal Medicine	https://doi.org/10.1007/s11606-020-05783-5
16.	Mind the Gap: Putting Evidence into Practice in the Era of the Learning Health System	Journal of General Internal Medicine	https://doi.org/10.1007/s11606-018-4633-1
17.	Murad MH, Fiordalisi C, Pillay J., et al. Making Narrative Statements to Describe Treatment Effects	Journal of General Internal Medicine	https://doi.org/10.1007/s11606-020-06330-y
18.	Reid E, Guise JM, Fiordalisi, et al. NxGen Evidence: Redesigning the Agency for Healthcare Research and Quality (AHRQ) Effective Health Care website to promote engagement, interactivity and usability of systematic reviews	Research Synthesis Methods	https://doi.org/10.1002/jrsm.1438
19.	Gartlehner G, Wagner G, Lux L, et al. Assessing the accuracy of machine-assisted abstract screening with DistillerAI: a user study.	Systematic Reviews	https://dx.doi.org/10.1186/s13643-019-1221-3.
20.	Gates A, Guitard S, Pillay J, et al. Performance and usability of machine learning for screening in systematic reviews: a comparative evaluation of three tools.	Systematic Reviews	https://dx.doi.org/10.1186/s13643-019-1222-2

Research Reports (7)

1.	Gartlehner G, Wagner G, Lux L, Affengruber L, Dobrescu A, Kaminski-Hartenthaler A, Viswanathan M. Assessing the Accuracy of Machine-Assisted Abstract Screening With DistillerAI: A User Study. Methods Research Report. AHRQ Publication No. 19(20)-EHC026-EF. Rockville, MD: Agency for Healthcare Research and Quality.	https://doi.org/10.23970/AHRQEPCMETHMACHINEDISTILLER
2.	Gates A, Guitard S, Pillay J, Elliott SA, Dyson MP, Newton AS, Hartling L. Performance and Usability of Machine Learning for Screening in Systematic Reviews: A Comparative Evaluation of Three Tools. (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. 290-2015-00001-I) AHRQ Publication No. 19(20)-EHC027-EF Rockville, MD: Agency for Healthcare Research and Quality.	https://doi.org/10.23970/AHRQEPCMETHMACHINEPERFORMANCE
3.	Lin J, Murad H, Leas B, et al. Integrating Health System Data with Systematic Reviews: A Framework for When and How Unpublished Health System Data Can Be Used with Systematic Reviews to Support Health System Decision Making.	https://doi.org/10.23970/AHRQEPCMETHQUALIMPRINTEGRATING
4.	Michel J, Flores E, Mull N, Tsou AY. Translation of a Clinical Pathway for C. Difficile Treatment Into a Machine-Readable Clinical Decision Support Artifact Prototyped for Electronic Health Record Integration.	https://doi.org/10.23970/AHRQEPCMETHQUALIMPRCDIFF.
5.	Michel J, Flores E, Mull N, Tsou AY. Translation of a Clinical Pathway for C. Difficile Treatment Into a Machine-Readable Clinical Decision Support Artifact Prototyped for Electronic Health Record Integration.	https://doi.org/10.23970/AHRQEPCMETHQUALIMPRCDIFF.
6.	Saldanha IJ, Senturk B, Smith BT, Robinson, KA. Pilot to Promote Entry of Structured Data Into the Systematic Review Data Repository.	https://doi.org/10.23970/AHRQEPCMETHQUALIMPRSRDR.
7.	Saldanha IJ, Senturk B, Smith BT, Robinson, KA. Pilot to Promote Entry of Structured Data Into the Systematic Review Data Repository.	https://doi.org/10.23970/AHRQEPCMETHQUALIMPRSRDR.

Methods Guidance (3)

White Papers (11)

Effective Health Care Data Visualizations/AHRQ Effective Health Care Website

The SRC has led the effort at AHRQ's EPC Program website to make program reports easier to use and understand by adding data visualizations and other improvements to the web-based display. This effort is ongoing:

Data Visualizations (7)

We can be reached by email at methods@epc-src.org.

1.	Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions	https://doi.org/10.23970/AHRQEPCMETHGUIDE2
2.	Prioritization and selection of harms for inclusion in systematic reviews	https://doi.org/10.23970/AHRQEPCMETHGUIDE1
3.	Quantitative Synthesis-An Update	https://doi.org/10.23970/AHRQEPCMETHGUIDE3

1.	A Framework for Conceptualizing Evidence Needs of Health Systems	https://doi.org/10.23970/AHRQEPCWHITEPAPER3
2.	Fiordalisi C, Borsky A, Chang S. Improving Health Systems' Access to High-Quality Evidence: AHRQ EPC 2018 Pilot Projects Summary.	https://doi.org/10.23970/AHRQEPCMETHENGAGESUMMARY
3.	Gerrity M, Fiordalisi C, Pillay J, et al. Roadmap for Narratively Describing Effects of Interventions in Systematic Reviews	https://doi.org/10.23970/AHRQEPCWHITEPAPERNARRATIVELY
4.	Hartling L, Gates A, Pillay J, et al. Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers.	https://doi.org/10.23970/AHRQEPCMETHENGAGEDEVELOPMENT.
5.	Lin JS, Rubenstein LV, Beil TL, et al. Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test of an Interactive, Web-Based Presentation and Discussion of Evidence.	https://doi.org/10.23970/AHRQEPCMETHENGAGELINKING
6.	Morrow AS, Butler M, Murad MH. Facilitating the Implementation of EPC Reports in Learning Health Systems Engaged in Quality Initiatives: an EPC Pilot Project on ADHD.	http://doi.org/10.23970/AHRQEPCMETHQUALIMPRFACILITATING
7.	Morrow AS, Whiteside SP, Sim L, et al. EPC Pilot Project: A Dual Approach To Facilitate Health Systems Uptake of Evidence Synthesis Reports.	https://doi.org/10.23970/AHRQEPCMETHENGAGEANXIETY
8.	Murad MH, Chang SM, Fiordalisi C, et al. Improving the Utility for Healthcare Decisionmakers of Evidence Synthesis in the Face of Insufficient Evidence	https://doi.org/10.23970/AHRQEPCWHITEPAPERIMPROVING
9.	Paynter RA, Fiordalisi C, Stoeger E, et al. A Prospective Comparison of Evidence Synthesis Search Strategies Developed With and Without Text-Mining Tools	https://doi.org/10.23970/AHRQEPCMETHODSPROSPECTIVECOMPARISON
10.	Robinson KA. Disseminating Findings From EPC Reports: Pilot Project of Three Products.	https://doi.org/10.23970/AHRQEPCMETHENGAGEDISSEM
11.	Understanding Health-Systems' Use of and Need for Evidence to Inform Decision-making	https://doi.org/10.23970/AHRQEPCWHITEPAPER2

1.	Antipsychotics for the Prevention and Treatment of Delirium	https://effectivehealthcare.ahrq.gov/products/antipsychotics/research
2.	Treatment of Depression in Children and Adolescents	https://effectivehealthcare.ahrq.gov/products/childhood-depression/research
3.	Interventions To Decrease Hospital Length of Stay	https://effectivehealthcare.ahrq.gov/products/hospital-length-of-stay/report
4.	Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain	https://effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment/living-review
5.	Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review	https://effectivehealthcare.ahrq.gov/products/immunity-after-covid/rapid-review
6.	Malnutrition in Hospitalized Adults	https://effectivehealthcare.ahrq.gov/products/malnutrition-hospitalized-adults/research
7.	Management of Primary Headaches in Pregnancy	https://effectivehealthcare.ahrq.gov/products/headaches-pregnancy/research